Tag Archives: tenofovir

African study confirms dolutegravir for second-line treatment and supports recycling of tenofovir

Dolutegravir or darunavir/ritonavir are equally effective in second-line treatment, even in the presence of high-level resistance to NRTIs included in the regimen, a large randomised study carried out in three African countries has found. Furthermore, tenofovir and lamivudine can be recycled in second-line treatment even in people with high-level resistance to the drugs, without undermining… Read More »

Meta-analysis finds no real difference in safety and effectiveness between tenofovir formulations

There are no real differences between tenofovir formulations – tenofovir disoproxil fumarate (TDF) and tenofovir alafenamide (TAF) – in terms of viral suppression and bone and renal safety, according to a systematic review and meta-analysis published in AIDS. The newer formulation of the drug (TAF) only showed superiority in terms of efficacy, and then to a modest… Read More »