Urgent Action Needed
Scientists worldwide are warning that without immediate action, antifungal resistance will become an even bigger problem. A recent study published in The Lancet, led by researchers from The University of Manchester, the Westerdijk Institute, and the University of Amsterdam, highlights the rising danger. Fungal pathogens now account for 3.8 million deaths yearly, and many are already resistant to antifungal drugs.
A Wider Focus is Needed
The scientists argue that while bacterial resistance is a major concern, fungal resistance is often overlooked. The United Nations’ upcoming meeting on antimicrobial resistance (AMR) in September must include discussions on fungal pathogens.
Serious Health Risks
Fungal infections, like those caused by Aspergillus, Candida, and Trichophyton indotineae, can be deadly, especially for older adults or those with weak immune systems. Dr. Norman van Rhijn from The University of Manchester emphasizes that fungal diseases are a growing global issue but are still not getting the attention they deserve.
Challenges in Treatment
One major difficulty is that fungi and human cells are very similar, making it hard to develop antifungal treatments that aren’t toxic to humans. Though new antifungal drugs are being developed, resistance to them can appear quickly, especially when similar compounds are used in agriculture.
Recommendations from Scientists
- Limit the use of certain antifungal drugs to specific areas.
- Work together globally to protect food, animals, and human health.
- Address fungal resistance during the UN’s AMR discussions in September.