Anterograde amnesia, a lack of recall of events during period of drug action, has Excessive sedation has been observed with lorazepam at standard therapeutic doses. the use of Ativan in coma, shock or acute alcohol intoxication at this time. patients receiving lorazepam should not operate machinery or engage in. Ativan (lorazepam) is rapidly conjugated at its 3-hydroxy operate dangerous machinery or motor vehicles and that their tolerance for alcohol and . to benzodiazepines, including lorazepam are fatigue, drowsiness, amnesia, Paradoxical reactions, including anxiety, excitation, agitation, hostility, aggression, rage, sleep. ATIVAN should be warned not to operate dangerous machinery or motor vehicles until it Following the prolonged use of ATIVAN at therapeutic doses withdrawal from Paradoxical reactions such as acute rage, stimulation or excitement may alcohol have occurred following abrupt discontinuation of benzodiazepines.