Jul 26, - Two commonly prescribed prescription painkillers are tramadol and Lortab, particularly when it comes to which is better for treating pain. Dec 14, - Oxycodone and tramadol are prescription medications used to manage moderate to severe pain. muscle relaxants, or benzodiazepines, for example, alprazolam (Xanax). Several Oxycodone is a strong narcotic pain-reliever and cough . (Flexeril); Benzodiazepines, for example, lorazepam (Ativan).Oxycodone vs. tramadol · What are oxycodone and · What are the uses for. Jul 25, - Valium and Xanax are both benzodiazepines, which are minor tranquilizers that can help with anxiety. Though they're similar, they're not.