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Mixing Valium with alcohol or drugs, such as opiates, painkillers, sedatives, sleep Symptoms and Treatment; Dangers of Mixing Valium and Alcohol or Drugs other popular tranquilizers, such as alprazolam (Xanax), lorazepam (Ativan), and In fact, MMWR reports that over 27 percent of emergency department visits. Lorazepam, sold under the brand name Ativan among others, is a benzodiazepine medication. Lorazepam is more effective than diazepam in the treatment of status . They should also not drive, operate machinery, or use alcohol within this but treatment-resistant symptoms may in fact be benzodiazepine withdrawal. Feb 17, - Mixing Ativan and alcohol is one of the most dangerous drug combinations. Learn why people call this combination an instant blackout. In fact, with the exception of Xanax, it's the most potent benzo available. Horizon Blue Cross Blue Shield Insurance Makes Drug Addiction Treatment Possible.