A US study has concluded that weight gain is greater by around 2 to 4 kg in HIV-positive people taking bictegravir or dolutegravir as part of their first antiretroviral therapy (ART), compared to their counterparts using other drug regimens. A similar effect was reported in those using the protease inhibitor darunavir. The study led by… Read More »
Chavey, MD, MS. In patients beginning hypertension monotherapy, diuretics are a more effective and safer option than angiotensin-converting enzyme ACE inhibitors, according to a large, retrospective, industry-funded analysis in The Lancet. Using nine healthcare databases from the U. The researchers examined nine effectiveness outcomes and 46 safety outcomes across the drug classes. Most effectiveness comparisons… Read More »
Treatments for HIV involve taking antiretroviral drugs. Protease inhibitors are one of seven classes of antiretroviral drugs. Antiretroviral drugs are designed to treat HIV. Different drugs have different mechanisms of action. Protease inhibitors work by blocking the activity of HIV protease, which is an enzyme that HIV needs to multiply. A healthcare professional usually prescribes… Read More »