Tag Archives: efavirenz

Efavirenz in pregnancy is at least as safe as other antiretrovirals

The European Pregnancy and Paediatric HIV Cohort Collaboration includes data from 24,963 pregnancies ending in singleton live births between 2002 and 2015. Cohorts in Belgium, Denmark, Germany, Ireland, Italy, the Netherlands, Poland, Romania, Spain, Sweden, Switzerland, Thailand, Ukraine and the United Kingdom provided data. In 1200 pregnancies (4.8%), the mother received efavirenz at the time… Read More »

Dolutegravir or lower-dose efavirenz equally effective, but less resistance with dolutegravir

Dolutegravir-based treatment was no more effective than treatment based on a 400mg dose of efavirenz, a randomised trial conducted in Cameroon has found. However, almost half of people with very high viral loads taking either regimen had a detectable viral load after 48 weeks, the HIV Glasgow 2018 conference heard. Despite the non-inferiority of efavirenz-based… Read More »